Ange Postecoglou will hope his Spurs can end a four-game winless streak when they face West Ham on Friday morning (7.15am AEDT).
Tottenham ended a run of three-straight losses in a 3-3 draw with Manchester City on the weekend, but a host of injuries have cruelled the early momentum that saw them rise to the top of the table in October.
Spurs were forced to name a makeshift back line without a recognised centre-back for the past two games, but will be boosted by the return of vice-captain Cristian Romero from a three-game ban.
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Postecoglou said: “It was not like he was the only one missing. All of a sudden post-Chelsea we lost Micky (Van de Ven), we lost Destiny (Udogie), we lost pretty much our whole back four, we lost Madders (James Maddison) and he knows how important he is.”