A 2-point improvement in pain based on a numeric rating scale may indicate that patients are responding to treatment for pyoderma gangrenosum.
To help determine whether a patient with pyoderma gangrenosum is responding to treatment, researchers used a patient global assessment (PGA) score to establish a minimal important difference (MID) in the measure of pain.
The MID was analyzed as median change in pain associated with each magnitude of absolute change in PGA score in 43 patients from a pyoderma gangrenosum registry at Oregon Health & Science University from June 2021 to June 2022.
PGA was the anchor measure, a 5-point scale in which patients described their skin condition as clear, almost clear, mild, moderate, or severe. Other data obtained from the registry included ulcer…